Article
The Oak Ridge Polycystic Kidney (orpk) disease gene is required for left-right axis determination.
Development (Cambridge, England) - 1 Jun 2000
Murcia N S, Richards W G, Yoder B K, Mucenski M L, Dunlap J R, Woychik R P
Abstract excerpt
Analysis of several mutations in the mouse is providing useful insights into the nature of the genes required for the establishment of the left-right axis during early development. Here we describe a new targeted allele of the mouse Tg737 gene, Tg737(Delta)2-3(beta)Gal), which causes defects in left-right asymmetry and other abnormalities during embryogenesis. The Tg737 gene was originally identified based on its...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.