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Article

Gut endoderm is involved in the transfer of left-right asymmetry from the node to the lateral plate mesoderm in the mouse embryo.

Development (Cambridge, England) - 1 Jul 2012

Saund Ranajeet S, Kanai-Azuma Masami, Kanai Yoshiakira, Kim Injune, Lucero Mary T, Saijoh Yukio

Abstract excerpt

In the mouse, the initial signals that establish left-right (LR) asymmetry are determined in the node by nodal flow. These signals are then transferred to the lateral plate mesoderm (LPM) through cellular and molecular mechanisms that are not well characterized. We hypothesized that endoderm might play a role in this process because it is tightly apposed to the node and covers the outer surface of the embryo,...

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Identifiers

PMID: 22627279
DOI: 10.1242/dev.079921
PMCID: PMC3367449

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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