Article
Association of IL-6 rs1800795, but not TNF-α rs1800629, and IL-1β rs16944 polymorphisms' genotypes with recovery of ischemic stroke patients following thrombolysis.
Neurological research - 1 Feb 2024
Dusanovic Pjevic Marija, Vojvodic Ljubica, Grk Milka, Todorovic Jovana, Maksimovic Nela, Rasic Milica, Perovic Dijana, Damnjanovic Tatjana, Trickovic Jelena, Kacar Katarina, Jekic Biljana
Abstract excerpt
OBJECTIVES: Inflammatory cytokines like tumor necrosis factor-α (TNF-α), interleukin (IL)-1β, and IL-6 can cause brain injury, slow recovery, and adverse effects (ADEs) in ischemic stroke (IS) patients treated with recombinant tissue plasminogen activator (rtPA). We explored the relationship between selected polymorphisms within TNF-α, IL-1β and IL-6 genes, and post-IS outcome and ADEs in patients treated with...
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