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Article

Glucocorticoids suppress selected components of the senescence-associated secretory phenotype.

Aging cell - 1 Aug 2012

Laberge Remi-Martin, Zhou Lili, Sarantos Melissa R, Rodier Francis, Freund Adam, de Keizer Peter L J, Liu Su, Demaria Marco, Cong Yu-Sheng, Kapahi Pankaj, Desprez Pierre-Yves, Hughes Robert E, Campisi Judith

Abstract excerpt

Cellular senescence suppresses cancer by arresting the proliferation of cells at risk for malignant transformation. Recently, senescent cells were shown to secrete numerous cytokines, growth factors, and proteases that can alter the tissue microenvironment and may promote age-related pathology. T...

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Identifiers

PMID: 22404905
DOI: 10.1111/j.1474-9726.2012.00818.x
PMCID: PMC3387333

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22404905-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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