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Article

Detection of the senescence-associated secretory phenotype (SASP).

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2013

Rodier Francis

Abstract excerpt

Cellular senescence suppresses cancer by eliminating potentially oncogenic cells, participates in tissue repair, contributes to cancer therapy, and promotes organismal aging. Numerous activities of senescent cells depend on the aptitude of these cells to secrete myriads of bioactive molecules, a behavior termed the senescence-associated secretory phenotype (SASP). The SASP supports cell-autonomous functions like...

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PMID: 23296657
DOI: 10.1007/978-1-62703-239-1_10

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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