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Article

BALB/c mice genetically susceptible to proteoglycan-induced arthritis and spondylitis show colony-dependent differences in disease penetrance.

Arthritis research & therapy - 1 Jan 2009

Farkas Balint, Boldizsar Ferenc, Tarjanyi Oktavia, Laszlo Anna, Lin Simon M, Hutas Gabor, Tryniszewska Beata, Mangold Aaron, Nagyeri Gyorgy, Rosenzweig Holly L, Finnegan Alison, Mikecz Katalin, Glant Tibor T

Abstract excerpt

INTRODUCTION: The major histocompatibility complex (H-2d) and non-major histocompatibility complex genetic backgrounds make the BALB/c strain highly susceptible to inflammatory arthritis and spondylitis. Although different BALB/c colonies develop proteoglycan-induced arthritis and proteoglycan-induced spondylitis in response to immunization with human cartilage proteoglycan, they show significant differences in...

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Source

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Identifiers

PMID: 19220900
DOI: 10.1186/ar2613
PMCID: PMC2688253

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Source receipt: pubmed, retrieved 7 Sept 2026.

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