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Article

Functional analysis of TCF7L2 genetic variants associated with type 2 diabetes.

Nutrition, metabolism, and cardiovascular diseases : NMCD - 1 Jun 2013

Pang D X, Smith A J P, Humphries S E

Abstract excerpt

BACKGROUND AND AIMS: Common non-coding variations within the TCF7L2 locus have a strong influence on type 2 diabetes (T2D) susceptibility through uncharacterised mechanisms. An islet-specific functional polymorphism has been identified, although this does not explain the association between genotype and gene expression in other cell types. This study sought to identify these other functional TCF7L2 variants....

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22402060
DOI: 10.1016/j.numecd.2011.12.012
PMCID: PMC3778915

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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