Article
Exon sequencing and association analysis of polymorphisms in TCF7L2 with type 2 diabetes in a Chinese population.
Diabetologia - 1 Jul 2008
Ren Q, Han X Y, Wang F, Zhang X Y, Han L C, Luo Y Y, Zhou X H, Ji L N
Abstract excerpt
AIMS/HYPOTHESIS: Recently, variants in the transcription factor 7-like 2 (TCF7L2) gene have been found to be consistently associated with type 2 diabetes in different populations. In this study, we hypothesized that TCF7L2 also contributed to genetic susceptibility for type 2 diabetes in a Chinese population. METHODS: We looked for new variants by direct sequencing of all exons and intron-exon junctions of TCF7L2...
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