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Article

The TCF7L2 locus and type 1 diabetes.

BMC medical genetics - 3 Aug 2007

Qu Hui-Qi, Polychronakos Constantin

Abstract excerpt

BACKGROUND: TCF7L2 belongs to a subfamily of TCF7-like HMG box-containing transcription factors, and maps to human chromosome 10q25.3. A recent study identified genetic association of type 2 diabetes (T2D) with this gene, correlated with diminished insulin secretion. This study aimed to investigate the possibility of genetic association between TCF7L2 and type 1 diabetes (T1D). METHODS: The SNP most significantly...

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Share to Genotype
Share to Polymorphism, Single Nucleotide
Share to TCF Transcription Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Diabetes Mellitus, Type 1

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Share to Genetic Predisposition to Disease

Share to Transcription Factor 7-Like 2 Protein

Source

Open in PubMed Open full text

Identifiers

PMID: 17683561
DOI: 10.1186/1471-2350-8-51
PMCID: PMC1978206

Genes

TCF7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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