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An integrated surrogate model for screening of drugs against Mycobacterium tuberculosis

7 Mar 2012

Abstract excerpt

OBJECTIVES: The intracellularly surviving and slow-growing pathogen, Mycobacterium tuberculosis, adapts the host cell environment for its active and dormant life cycle. It is evident that the lack of appropriate high-throughput screening of inhibitors within host cells is an impediment for the early stages of anti-tubercular drug discovery. We aimed to develop an integrated surrogate model that enhances the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 22398649
DOI: 10.1093/jac/dks056

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