Article
Phenotypic and genomic comparison of Mycobacterium aurum and surrogate model species to Mycobacterium tuberculosis: implications for drug discovery.
BMC genomics - 13 Jul 2017
Namouchi Amine, Cimino Mena, Favre-Rochex Sandrine, Charles Patricia, Gicquel Brigitte
Abstract excerpt
BACKGROUND: Tuberculosis (TB) is caused by Mycobacterium tuberculosis and represents one of the major challenges facing drug discovery initiatives worldwide. The considerable rise in bacterial drug resistance in recent years has led to the need of new drugs and drug regimens. Model systems are regularly used to speed-up the drug discovery process and circumvent biosafety issues associated with manipulating M....
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