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Article

Targeted Inactivation of Snail Family EMT Regulatory Factors by a Co(III)-Ebox Conjugate

29 Feb 2012

Abstract excerpt

Snail family proteins are core EMT (epithelial-mesenchymal transition) regulatory factors that play essential roles in both development and disease processes and have been associated with metastasis in carcinomas. Snail factors are required for the formation of neural crest stem cells in most vertebrate embryos, as well as for the migratory invasive behavior of these cells. Snail factors have recently been linked...

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PMID: 22393397
DOI: 10.1371/journal.pone.0032318

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