Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?

Nature reviews. Cancer - 1 Jun 2007

Peinado Héctor, Olmeda David, Cano Amparo

Abstract excerpt

The molecular mechanisms that underlie tumour progression are still poorly understood, but recently our knowledge of particular aspects of some of these processes has increased. Specifically, the identification of Snail, ZEB and some basic helix-loop-helix (bHLH) factors as inducers of epithelial-mesenchymal transition (EMT) and potent repressors of E-cadherin expression has opened new avenues of research with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cadherins
Share to Cell Adhesion
Share to Epithelium

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Helix-Turn-Helix Motifs

Share to Neoplasm Invasiveness

Share to Protein Processing, Post-Translational

Share to Snail Family Transcription Factors

Share to Zinc Finger E-box-Binding Homeobox 1

Source

Identifiers

PMID: 17508028
DOI: 10.1038/nrc2131

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?PMID 17508028Read ↗

The Role of Snail in EMT and TumorigenesisSemantic proximity Read ↗

The Snail Family in Normal and Malignant Haematopoiesis.Semantic proximity Read ↗

Zeb1 and Snail1 engage miR-200f transcriptional and epigenetic regulation during EMT.Semantic proximity Read ↗

Central role of Snail1 in the regulation of EMT and resistance in cancer: a target for therapeutic interventionSemantic proximity Read ↗

The Snail genes as inducers of cell movement and survival: implications in development and cancerSemantic proximity Read ↗

The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression.Semantic proximity Read ↗

Epigenetic Regulation of EMT: The Snail StorySemantic proximity Read ↗

An "unexpected" role for EMT transcription factors in hematological development and malignancySemantic proximity Read ↗

Non-canonical functions of SNAIL drive context-specific cancer progressionSemantic proximity Read ↗

Defining the E-Cadherin Repressor Interactome in Epithelial-Mesenchymal Transition: The PMC42 Model as a Case StudySemantic proximity Read ↗

Snail induction of epithelial to mesenchymal transition in tumor cells is accompanied by MUC1 repression and ZEB1 expression.Semantic proximity Read ↗

The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.