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Article

Expression of the zinc-finger transcription factor Snail in adrenocortical carcinoma is associated with decreased survival

18 Nov 2008

Abstract excerpt

In this study, we evaluate whether Snail is expressed in adrenocortical cancer (ACC) and if its expression is related to patient outcome. One of the best known functions of the zinc-finger transcription factor Snail is to induce epithelial-to-mesenchymal transition (EMT). Increasing evidence suggests that EMT plays a pivotal role in tumour progression and metastatic spread. Snail and E-cadherin expression were...

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Share to Cancer, Hypoxia, and Metabolism
Share to Adrenal and Paraganglionic Tumors
Share to Epigenetics and DNA Methylation

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PMID: 19018264
DOI: 10.1038/sj.bjc.6604755

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