Article
A common variant near TERC and telomere length are associated with susceptibility to childhood acute lymphoblastic leukemia in Chinese.
Leukemia & lymphoma - 1 Sept 2012
Sheng Xiaojing, Zhang Limei, Luo Dewei, Tong Na, Wang Meilin, Fang Yongjun, Li Jie, Zhang Zhengdong
Abstract excerpt
Telomeres are involved in maintaining chromosomal stability, cellular immortality and tumorigenesis. A recent genome-wide association study has identified an association between telomere length and two common variants (rs12696304 and rs16847897) at 3q26 that includes TERC. We hypothesized that the two variants and relative telomere length (RTL) would be predictors of the risk of childhood acute lymphoblastic...
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