Article
Leukocyte Telomere Length Shortening, hTERT Genetic Polymorphisms and Risk of Childhood Acute Lymphoblastic Leukemia
Asian Pacific journal of cancer prevention : APJCP - 25 Jun 2018
Eskandari Ebrahim, Hashemi Mohammad, Naderi Majid, Bahari Gholamreza, Safdari Vahid, Taheri Mohsen
Abstract excerpt
Background: Telomeres are involved in chromosomal stability, cellular immortality and tumorigenesis. Human telomerase reverse transcriptase (TERT) is essential for the maintenance of telomere DNA length. Recently, a variable tandem-repeats polymorphism, MNS16A, located in the downstream region of the TERT gene, was reported to have an effect on TERT expression and telomerase activity. Previous studies have linked...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
