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Article

TERT polymorphisms modify the risk of acute lymphoblastic leukemia in Chinese children.

Carcinogenesis - 1 Jan 2013

Sheng Xiaojing, Tong Na, Tao Guoquan, Luo Dewei, Wang Meilin, Fang Yongjun, Li Jie, Xu Ming, Zhang Zhengdong, Wu Dongmei

Abstract excerpt

Human telomerase reverse transcriptase (TERT) is essential for the maintenance of telomere DNA length, chromosomal stability and cellular immortality. We hypothesized that TERT polymorphisms are associated with risk of childhood acute lymphoblastic leukemia (ALL). We first conducted a case-control study of 570 ALL cases and 673 cancer-free controls of Chinese children, using the tagging single-nucleotide...

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Identifiers

PMID: 23066086
DOI: 10.1093/carcin/bgs325

Genes

TERT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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