Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Signaling mechanisms of LOV domains: new insights from molecular dynamics studies.

Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology - 1 Jul 2013

Freddolino Peter L, Gardner Kevin H, Schulten Klaus

Abstract excerpt

Phototropins are one of several classes of photoreceptors used by plants and algae to respond to light. These proteins contain flavin-binding LOV (Light-Oxygen-Voltage) domains that form covalent cysteine-flavin adducts upon exposure to blue light, leading to the enhancement of phototropin kinase activity. Several lines of evidence suggest that adduct formation in the phototropin LOV2 domains leads to the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Avena
Share to Binding Sites

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cluster Analysis

Share to Databases, Protein

Share to Glutamine

Share to Molecular Dynamics Simulation

Share to Protein Structure, Secondary

Source

Open in PubMed Open full text

Identifiers

PMID: 23407663
DOI: 10.1039/c3pp25400c
PMCID: PMC3679247

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Signaling mechanisms of LOV domains: new insights from molecular dynamics studies.PMID 23407663Read ↗

Unraveling the Mechanism of a LOV Domain Optogenetic Sensor: A Glutamine Lever Induces Unfolding of the Jα Helix.Semantic proximity Read ↗

Disruption of the LOV-Jalpha helix interaction activates phototropin kinase activity.Semantic proximity Read ↗

Mechanism-based tuning of a LOV domain photoreceptor.Semantic proximity Read ↗

Time-resolved Fourier transform infrared study on photoadduct formation and secondary structural changes within the phototropin LOV domain.Semantic proximity Read ↗

Steric and Electronic Interactions at Gln154 in ZEITLUPE Induce Reorganization of the LOV Domain Dimer Interface.Semantic proximity Read ↗

The photocycle of a flavin-binding domain of the blue light photoreceptor phototropin.Semantic proximity Read ↗

Investigating models of protein function and allostery with a widespread mutational analysis of a light-activated protein.Semantic proximity Read ↗

Light signal transduction pathway from flavin chromophore to the J alpha helix of Arabidopsis phototropin1.Semantic proximity Read ↗

Unusual photodynamic characteristics of the light-oxygen-voltage domain of phototropin linked to terrestrial adaptation of Klebsormidium nitens.Semantic proximity Read ↗

Phototropin LOV domains exhibit distinct roles in regulating photoreceptor function.Semantic proximity Read ↗

A search for radical intermediates in the photocycle of LOV domains.Semantic proximity Read ↗

TULIPs: tunable, light-controlled interacting protein tags for cell biology.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.