Article
Isoniazid acetylation phenotyping in Saudi Arabs.
Journal of clinical pharmacy and therapeutics - 1 Oct 2004
Matar K M, Mayet A Y, Ayoola E A, Bawazir S A, Al-Faleh F Z, Al-Wazzan A
Abstract excerpt
AIMS: The present study is designed to investigate the acetylator status in Saudi Arabs. METHODS: Isoniazid (INH) acetylation phenotyping was studied in 136 Saudi Arabs in Riyadh, Saudi Arabia, using a single plasma sample taken 3 h post-INH oral dose of 200 mg. Metabolic ratio (MR) of plasma acetyl-INH (Ac-INH) to INH was used to determine the acetylation phenotype. RESULTS: The MR had a bimodal distribution...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
