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Article

Estrogen-metabolizing gene polymorphisms in the assessment of female hormone-dependent cancer risk.

The pharmacogenomics journal - 1 Jan 2000

Mikhailova O N, Gulyaeva L F, Prudnikov A V, Gerasimov A V, Krasilnikov S E

Abstract excerpt

Allelic variants of cytochrome P450: CYP1A1, CYP1A2, CYP19 (Aromatase) and II-phase enzyme Sulfotransferase (SULT1A1) genes are associated with a high risk of hormone-dependent cancers. We estimated a frequency of these allelic variants in the female Caucasian population of the Novosibirsk region of Russia and their association with the elevated risk of ovarian and endometrial cancer. A DNA bank of gynecologic...

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Identifiers

PMID: 16402077
DOI: 10.1038/sj.tpj.6500365

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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