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Article

Cytochrome P450 1A1, cigarette smoking, and risk of endometrial cancer (United States).

Cancer causes & control : CCC - 1 Dec 2007

McGrath Monica, Hankinson Susan E, De Vivo Immaculata

Abstract excerpt

Cytochrome P450 1A1 (CYP1A1) is involved in the metabolism of estradiol and the activation of polycyclic aromatic hydrocarbons found in tobacco products. Polymorphic variation in CYP1A1 activity may modify susceptibility to endometrial cancer through the oxidative metabolism of estradiol and the activation of tobacco-smoke constituents. We prospectively evaluated the associations between three common CYP1A1...

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Identifiers

PMID: 17717632
DOI: 10.1007/s10552-007-9051-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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