Article
CYP1B1 gene in endometrial cancer.
Molecular and cellular endocrinology - 28 Apr 2003
Sasaki Masahiro, Kaneuchi Masanori, Fujimoto Seiichiro, Tanaka Yuichiro, Dahiya Rajvir
Abstract excerpt
Metabolic activation of estradiol has been shown to be a key factor in endometrial carcinogenesis. 4-hydroxy estrogens (CYP1B1 metabolites) received particular attention because of their causative role in malignant transformation of various organs including endometrium. CYP1B1 displays the highes...
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