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Article

Replication of an adenovirus type 34 mutant DNA containing tandem reiterations of the inverted terminal repeat.

Virology - 1 Dec 1990

Chen M, Horwitz M S

Abstract excerpt

A mutant of human adenovirus type 34 (Ad34) has been isolated which contains DNA molecules with tandem reiterations of from two to eight copies of a 131-bp sequence within the right-sided inverted terminal repetition. Terminal heterogeneity was not eliminated by repeated plaque purifications indicating that the population of DNA molecules with various numbers of reiterations could rapidly evolve from the DNA of a...

Topics

Adenoviruses, Human
Base Sequence
DNA, Viral
HeLa Cells
Humans
In Vitro Techniques
Molecular Sequence Data
Mutation
Repetitive Sequences, Nucleic Acid
Restriction Mapping
Virus Replication

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 2238462
DOI: 10.1016/0042-6822(90)90123-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2238462-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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