Article
A mutant of canine adenovirus type 2 with a duplication of the E1a region exhibits altered expression of early region 4.
The Journal of general virology - 1 Sept 1991
Cavanagh H M, Gallagher C F, Spibey N
Abstract excerpt
The genomic DNA of a vaccine strain of canine adenovirus type 2 (Vaxitas; ICI Tasman) has been shown to contain two copies of the E1a region, the second being at the far right end of the genome. DNA sequence analysis of the right terminal 2.8 kbp of this vaccine strain showed that numerous point...
Topics
- Adenoviridae
- Adenovirus Early Proteins
- Animals
- Base Sequence
- Cloning, Molecular
- DNA, Viral
- Dogs
- Gene Expression Regulation, Viral
- Molecular Sequence Data
- Multigene Family
- Mutation
- Oncogene Proteins, Viral
- Plasmids
- Promoter Regions, Genetic
- Restriction Mapping
- Transfection