Article
Cooperation of p300 and PCAF in the control of microRNA 200c/141 transcription and epithelial characteristics.
PloS one - 1 Jan 2012
Mizuguchi Yoshiaki, Specht Susan, Lunz John G, Isse Kumiko, Corbitt Natasha, Takizawa Toshihiro, Demetris Anthony J
Abstract excerpt
Epithelial to mesenchymal transition (EMT) not only occurs during embryonic development and in response to injury, but is an important element in cancer progression. EMT and its reverse process, mesenchymal to epithelial transition (MET) is controlled by a network of transcriptional regulators and can be influenced by posttranscriptional and posttranslational modifications. EMT/MET involves many effectors that...
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