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Article

Effects of rearrangement and allelic exclusion of JJAZ1/SUZ12 on cell proliferation and survival.

Proceedings of the National Academy of Sciences of the United States of America - 11 Dec 2007

Li Hui, Ma Xianyong, Wang Jinglan, Koontz Jason, Nucci Marisa, Sklar Jeffrey

Abstract excerpt

Polycomb group genes (PcGs) have been implicated in cancer based on altered levels of expression observed in certain tumors and the behavior of cultured cells containing inserted PcG transgenes. Endometrial stromal tumors provide evidence for a direct causal relationship because they contain several chromosomal translocations and resultant gene fusions involving PcGs, the most common of which joins portions of...

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Source

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Identifiers

PMID: 18077430
DOI: 10.1073/pnas.0709986104
PMCID: PMC2148412

Genes

JAZF1
SUZ12

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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