Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The transcriptional coactivator and acetyltransferase p300 in fibroblast biology and fibrosis

8 Jun 2007

Abstract excerpt

The transcriptional coactivator p300 is a ubiquitous nuclear phosphoprotein and transcriptional cofactor with intrinsic acetyltransferase activity. p300 controls the expression of numerous genes in cell-type and signal-specific manner, and plays a pivotal role in cellular proliferation, apoptosis, and embryogenesis. By catalyzing acetylation of histones and transcription factors, p300 plays a significant role in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic factors in colorectal cancer
Share to NF-κB Signaling Pathways
Share to TGF-β signaling in diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 17559085
DOI: 10.1002/jcp.21162

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The transcriptional coactivator and acetyltransferase p300 in fibroblast biology and fibrosisPMID 17559085Read ↗

EP300 as a Molecular Integrator of Fibrotic Transcriptional ProgramsSemantic proximity Read ↗

Biological role of p300 in cardiac myocytes.Semantic proximity Read ↗

The histone acetyl transferases CBP and p300 regulate stress response pathways in synovial fibroblasts at transcriptional and functional levelsSemantic proximity Read ↗

Life and death of transcriptional co-activator p300Semantic proximity Read ↗

Essential function of p300 acetyltransferase activity in heart, lung and small intestine formation.Semantic proximity Read ↗

Acetyltransferase p300 Is a Putative Epidrug Target for Amelioration of Cellular Aging-Related Cardiovascular DiseaseSemantic proximity Read ↗

Transcription coactivator p300 binds PCNA and may have a role in DNA repair synthesis.Semantic proximity Read ↗

Differential contribution of p300 and CBP to regulatory element acetylation in mESCsSemantic proximity Read ↗

Dysregulation of the p300/CBP histone acetyltransferases in human cancer.Semantic proximity Read ↗

CBP/p300 Drives the Differentiation of Regulatory T Cells through Transcriptional and Non-Transcriptional MechanismsSemantic proximity Read ↗

Immunohistochemical evaluation of phosphorylated SMAD2/SMAD3 and the co-activator P300 in human glomerulonephritis: correlation with renal injurySemantic proximity Read ↗

Cardiac p300 Is Involved in Myocyte Growth with Decompensated Heart FailureSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.