Article
An integrated approach of comparative genomics and heritability analysis of pig and human on obesity trait: evidence for candidate genes on human chromosome 2.
BMC genomics - 19 Dec 2012
Kim Jaemin, Lee Taeheon, Kim Tae-Hun, Lee Kyung-Tai, Kim Heebal
Abstract excerpt
BACKGROUND: Traditional candidate gene approach has been widely used for the study of complex diseases including obesity. However, this approach is largely limited by its dependence on existing knowledge of presumed biology of the phenotype under investigation. Our combined strategy of comparative genomics and chromosomal heritability estimate analysis of obesity traits, subscapular skinfold thickness and...
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