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Article

A powerful and flexible multilocus association test for quantitative traits.

American journal of human genetics - 1 Feb 2008

Kwee Lydia Coulter, Liu Dawei, Lin Xihong, Ghosh Debashis, Epstein Michael P

Abstract excerpt

Association mapping of complex traits typically employs tagSNP genotype data to identify a trait locus within a region of interest. However, considerable debate exists regarding the most powerful strategy for utilizing such tagSNP data for inference. A popular approach tests each tagSNP within the region individually, but such tests could lose power as a result of incomplete linkage disequilibrium between the...

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Share to Chromosome Mapping
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Share to Models, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Single Nucleotide

Share to Quantitative Trait, Heritable

Share to Quantitative Trait Loci

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Identifiers

PMID: 18252219
DOI: 10.1016/j.ajhg.2007.10.010
PMCID: PMC2664991

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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