Article
Defining genetic determinants of the Metabolic Syndrome in the Framingham Heart Study using association and structural equation modeling methods
1 Dec 2009
Abstract excerpt
The Metabolic Syndrome (MetSyn), which is a clustering of traits including insulin resistance, obesity, hypertension and dyslipidemia, is estimated to have a substantial genetic component, yet few specific genetic targets have been identified. Factor analysis, a sub-type of structural equation modeling (SEM), has been used to model the complex relationships in MetSyn. Therefore, we aimed to define the genetic...
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