Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Drosophila miR-124 regulates neuroblast proliferation through its target anachronism.

Development (Cambridge, England) - 1 Apr 2012

Weng Ruifen, Cohen Stephen M

Abstract excerpt

MicroRNAs (miRNAs) have been implicated as regulators of central nervous system (CNS) development and function. miR-124 is an evolutionarily ancient, CNS-specific miRNA. On the basis of the evolutionary conservation of its expression in the CNS, miR-124 is expected to have an ancient conserved function. Intriguingly, investigation of miR-124 function using antisense-mediated miRNA depletion has produced divergent...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Lineage
Share to Central Nervous System
Share to Crosses, Genetic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to In Situ Hybridization, Fluorescence

Share to MicroRNAs

Share to Microscopy, Fluorescence

Share to Stem Cells

Share to Transgenes

Source

Identifiers

PMID: 22378639
DOI: 10.1242/dev.075143

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Drosophila miR-124 regulates neuroblast proliferation through its target anachronism.PMID 22378639Read ↗

The Drosophila anachronism locus: a glycoprotein secreted by glia inhibits neuroblast proliferation.Semantic proximity Read ↗

Neurophysiological defects and neuronal gene deregulation in Drosophila mir-124 mutants.Semantic proximity Read ↗

Mutation of the central nervous system neuroblast proliferation repressor ana leads to defects in larval olfactory behavior.Semantic proximity Read ↗

miR-124 controls Drosophila behavior and is required for neural development.Semantic proximity Read ↗

The miR-124 family of microRNAs is crucial for regeneration of the brain and visual system in the planarian Schmidtea mediterranea.Semantic proximity Read ↗

The Nesprin family member ANC-1 regulates synapse formation and axon termination by functioning in a pathway with RPM-1 and β-Catenin.Semantic proximity Read ↗

The lin-4 microRNA targets the LIN-14 transcription factor to inhibit netrin-mediated axon attraction.Semantic proximity Read ↗

Control of proliferation activation in quiescent neuroblasts of the Drosophila central nervous system.Semantic proximity Read ↗

miR-989 is required for border cell migration in the Drosophila ovary.Semantic proximity Read ↗

Makorin-2 is a neurogenesis inhibitor downstream of phosphatidylinositol 3-kinase/Akt (PI3K/Akt) signal.Semantic proximity Read ↗

Normal function of the mushroom body defect gene of Drosophila is required for the regulation of the number and proliferation of neuroblasts.Semantic proximity Read ↗

The brain tumor gene negatively regulates neural progenitor cell proliferation in the larval central brain of Drosophila.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.