Article
miR-124 controls Drosophila behavior and is required for neural development.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience - 1 Nov 2014
Wang Chao, Feng Tongbao, Wan Qian, Kong Yan, Yuan Liudi
Abstract excerpt
MicroRNA-124 (miR-124) is an evolutionarily conserved, small, noncoding RNA molecule that participates in the central nervous system (CNS) developmental control of gene expression. In the current study, we found that Drosophila embryos lacking the mir-124 gene did not exhibit detectable defects in axon growth or CNS development. On the other hand, adult mutants showed severe problems in locomotion, flight, and...
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