Article
miR-989 is required for border cell migration in the Drosophila ovary.
PloS one - 1 Jan 2013
Kugler Jan-Michael, Verma Pushpa, Chen Ya-Wen, Weng Ruifen, Cohen Stephen M
Abstract excerpt
microRNAs (miRNAs) are small non-coding RNAs that regulate gene expression by destabilizing target transcripts and/or inhibiting their translation. miRNAs are thought to have roles in buffering gene expression to confer robustness. miRNAs have been shown to play important roles during tissue development to control cell proliferation, differentiation and morphogenesis. Many miRNAs are expressed in the germ line of...
Topics
- Animals
- Animals, Genetically Modified
- Cell Movement
- Drosophila
- Female
- Gene Expression
- Gene Expression Regulation, Developmental
- MicroRNAs
- Morphogenesis
- Mutation
- Oogenesis