Article
The miR-124 family of microRNAs is crucial for regeneration of the brain and visual system in the planarian Schmidtea mediterranea.
Development (Cambridge, England) - 15 Sept 2017
Sasidharan Vidyanand, Marepally Srujan, Elliott Sarah A, Baid Srishti, Lakshmanan Vairavan, Nayyar Nishtha, Bansal Dhiru, Sánchez Alvarado Alejandro, Vemula Praveen Kumar, Palakodeti Dasaradhi
Abstract excerpt
Brain regeneration in planarians is mediated by precise spatiotemporal control of gene expression and is crucial for multiple aspects of neurogenesis. However, the mechanisms underpinning the gene regulation essential for brain regeneration are largely unknown. Here, we investigated the role of the miR-124 family of microRNAs in planarian brain regeneration. The miR-124 family (miR-124) is highly conserved in...
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