Article
The Drosophila anachronism locus: a glycoprotein secreted by glia inhibits neuroblast proliferation.
Cell - 16 Jul 1993
Ebens A J, Garren H, Cheyette B N, Zipursky S L
Abstract excerpt
The Drosophila anachronism (ana) locus controls the proliferation of neuroblasts, neuronal stem cells that give rise to the central nervous system. In ana mutants, quiescent postembryonic central brain and optic lobe neuroblasts enter S phase precociously. ana encodes a novel secreted protein of...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Brain
- Cell Differentiation
- Cell Division
- Cells, Cultured
- DNA Mutational Analysis
- Drosophila
- Drosophila Proteins
- Glycoproteins
- Molecular Sequence Data
- Mutation
- Neuroglia
- Neurons
- Stem Cells