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IL‑13 and FOXO3 genes polymorphisms regulate IgE levels in asthmatic patients

13 Apr 2021

Abstract excerpt

Immunoglobulin E (IgE) serves a crucial role in the pathogenesis of several allergic disorders, and elevated levels of total serum IgE have been associated with asthma. IgE is responsible for the release of several asthma-associated inflammatory mediators from mast cells, such as histamine and prostaglandins. The aim of the present study was to assess the association of interleukin (IL)-13 single nucleotide...

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Identifiers

PMID: 33884198
DOI: 10.3892/br.2021.1431

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