Article
[Correlation of IL-4 and IL-13 gene polymorphisms with asthma and total serum IgE levels].
Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases - 1 Mar 2009
Wang Xiu-Hai, Zhao Wei, Liu Shi-Guo, Feng Xiao-Ping
Abstract excerpt
OBJECTIVE: To investigate the correlation between the single nucleotide polymorphisms (SNP) of +33C/T in the promoter region of IL-4 gene and +1923C/T in intron-3 region of IL-13 gene and the susceptibility of asthma, and to study the impact of these polymorphisms upon total serum IgE levels. METHODS: The 2 polymorphisms were determined by polymerase chain reaction and restriction fragment length polymorphism...
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