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Article

Study of gene-gene interactions for endophenotypic quantitative traits in Chinese asthmatic children.

Allergy - 1 Aug 2008

Chan I H S, Tang N L S, Leung T F, Huang W, Lam Y Y O, Li C Y, Wong C K, Wong G W K, Lam C W K

Abstract excerpt

BACKGROUND: Asthma is a complex disease resulting from interactions between multiple genes and environmental factors. Study of gene-gene interactions could provide insight into the pathophysiology of asthma. METHODS: We investigated the interactions among 18 single-nucleotide polymorphisms in eight candidate genes for plasma total immunoglobulin E (IgE) concentration and peripheral blood (PB) eosinophil count in...

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PMID: 18691306
DOI: 10.1111/j.1398-9995.2008.01639.x

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