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Article

Association of polymorphisms in genes encoding IL-4, IL-13 and their receptors with atopic dermatitis in a Korean population.

Experimental dermatology - 1 Nov 2011

Namkung Jung-Hyun, Lee Jong-Eun, Kim Eugene, Kim Hyun-Je, Seo Eun-Young, Jang Hye-Yoon, Shin Eun-Soon, Cho Eun-Young, Yang Jun-Mo

Abstract excerpt

Th2-dominated immune responses are believed to contribute to the pathogenesis of atopic dermatitis (AD). IL-4 and IL-13 are typical pleiotropic Th2 cytokines that play a central role in IgE-dependent inflammatory reactions. Single-nucleotide polymorphisms (SNPs) in IL-4 and IL-13 have been reported in patients with allergic disease from numerous countries. Gene-gene interactions among genes have been identified...

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Identifiers

PMID: 21913997
DOI: 10.1111/j.1600-0625.2011.01357.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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