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Article

Genome-wide association study of genetic determinants of LDL-c response to atorvastatin therapy: importance of Lp(a).

Journal of lipid research - 1 May 2012

Deshmukh Harshal A, Colhoun Helen M, Johnson Toby, McKeigue Paul M, Betteridge D John, Durrington Paul N, Fuller John H, Livingstone Shona, Charlton-Menys Valentine, Neil Andrew, Poulter Neil, Sever Peter, Shields Denis C, Stanton Alice V, Chatterjee Aurobindo, Hyde Craig, Calle Roberto A, DeMicco David A, Trompet Stella, Postmus Iris, Ford Ian, Jukema J Wouter, Caulfield Mark, Hitman Graham A

Abstract excerpt

We carried out a genome-wide association study (GWAS) of LDL-c response to statin using data from participants in the Collaborative Atorvastatin Diabetes Study (CARDS; n = 1,156), the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT; n = 895), and the observational phase of ASCOT (n = 651), all o...

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Source

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Identifiers

PMID: 22368281
DOI: 10.1194/jlr.P021113
PMCID: PMC3329377

Genes

LPA
APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22368281-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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