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Article

Inhibition of neuroblastoma cell growth by TREX1-mutated human lymphocytes.

Oncology reports - 1 May 2012

Pulliero A, Marengo B, Domenicotti C, Longobardi M G, Fazzi E, Orcesi S, Bianchi M, Balottin U, Izzotti A

Abstract excerpt

T lymphocytes play a major role in counteracting cancer occurrence and development. Immune therapies against cancer are focused on eliciting a cytotoxic T cell response. This anticancer activity is related to a variety of mechanisms including the activation of cytokines and proapoptotic mediators. Interferon α is an established inhibitor of cancer cell growth. A...

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Source

Identifiers

PMID: 22367235
DOI: 10.3892/or.2012.1696

Genes

TREX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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Inhibition of neuroblastoma cell growth by TREX1-mutated human lymphocytes.PMID 22367235Read ↗

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