Article
MKP-1 coordinates ordered macrophage-phenotype transitions essential for stem cell-dependent tissue repair.
Cell cycle (Georgetown, Tex.) - 1 Mar 2012
Perdiguero Eusebio, Kharraz Yacine, Serrano Antonio L, Muñoz-Cánoves Pura
Abstract excerpt
Re-establishing tissue homoeostasis in response to injury requires infiltration of inflammatory cells and activation of resident stem cells. However, full tissue recovery also requires that the inflammation is resolved. While it is known that disturbing the interactions between inflammatory cells and tissue resident cells prevents successful healing, the molecular mechanisms underlying the paracrine interactions...
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