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Article

Macrophage activation and skeletal muscle healing following traumatic injury.

The Journal of pathology - 1 Feb 2014

Novak Margaret L, Weinheimer-Haus Eileen M, Koh Timothy J

Abstract excerpt

Following injury to different tissues, macrophages can contribute to both regenerative and fibrotic healing. These seemingly contradictory roles of macrophages may be related to the markedly different phenotypes that macrophages can assume upon exposure to different stimuli. We hypothesized that fibrotic healing after traumatic muscle injury would be dominated by a pro-fibrotic M2a macrophage phenotype, with M1...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24255005
DOI: 10.1002/path.4301
PMCID: PMC4019602

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