Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ionophore-resistant mutant of Toxoplasma gondii reveals involvement of a sodium/hydrogen exchanger in calcium regulation.

The Journal of cell biology - 7 Jun 2004

Arrizabalaga Gustavo, Ruiz Felix, Moreno Silvia, Boothroyd John C

Abstract excerpt

Calcium is a critical mediator of many intracellular processes in eukaryotic cells. In the obligate intracellular parasite Toxoplasma gondii, for example, a rise in [Ca2+] is associated with significant morphological changes and rapid egress from host cells. To understand the mechanisms behind such dramatic effects, we isolated a mutant that is altered in its responses to the Ca2+ ionophore A23187 and found the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amiloride
Share to Calcimycin
Share to Calcium Signaling

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Ion Channels

Share to Ionophores

Share to Protons

Share to Sodium-Hydrogen Exchangers

Share to Toxoplasma

Source

Open in PubMed Open full text

Identifiers

PMID: 15173192
DOI: 10.1083/jcb.200309097
PMCID: PMC2172388

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ionophore-resistant mutant of Toxoplasma gondii reveals involvement of a sodium/hydrogen exchanger in calcium regulation.PMID 15173192Read ↗

Ionophore-resistant mutants of Toxoplasma gondii reveal host cell permeabilization as an early event in egress.Semantic proximity Read ↗

A novel dense granule protein, GRA41, regulates timing of egress and calcium sensitivity inToxoplasma gondiiSemantic proximity Read ↗

A Toxoplasma gondii mutant defective in responding to calcium fluxes shows reduced in vivo pathogenicity.Semantic proximity Read ↗

A forward genetic screen identifies a negative regulator of rapid Ca2+-dependent cell egress (MS1) in the intracellular parasite Toxoplasma gondiiSemantic proximity Read ↗

Artemisinin-resistant mutants of Toxoplasma gondii have altered calcium homeostasis.Semantic proximity Read ↗

A genetic screen to isolate Toxoplasma gondii host-cell egress mutants.Semantic proximity Read ↗

Calcium-dependent protein kinase 1 is an essential regulator of exocytosis in Toxoplasma.Semantic proximity Read ↗

Toxoplasma gondii: induction of egress by the potassium ionophore nigericin.Semantic proximity Read ↗

Identification of Intracellular and Plasma Membrane Calcium Channel Homologues in Pathogenic ParasitesSemantic proximity Read ↗

Characterization of a novel organelle in Toxoplasma gondii with similar composition and function to the plant vacuoleSemantic proximity Read ↗

An extracellular redox signal triggers calcium release and impacts the asexual development of <i>Toxoplasma gondii</i>Semantic proximity Read ↗

A plastid two-pore channel essential for inter-organelle communication and growth of Toxoplasma gondii.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.