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Article

A Toxoplasma gondii mutant defective in responding to calcium fluxes shows reduced in vivo pathogenicity.

Molecular and biochemical parasitology - 1 Oct 2007

Lavine Mark D, Knoll Laura J, Rooney Peggy J, Arrizabalaga Gustavo

Abstract excerpt

Toxoplasma gondii is an important opportunistic pathogen in immunocompromised individuals. Successful propagation in an infected host by this obligate intracellular parasite depends on its ability to enter and exit host cells. Egress from the cell can be artificially induced by causing fluxes of calcium within the parasite with the use of calcium ionophores. While this ionophore-induced egress (IIE) has been...

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Identifiers

PMID: 17643508
DOI: 10.1016/j.molbiopara.2007.06.004
PMCID: PMC2034501

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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