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Excision of HIV-1 Proviral DNA by Recombinant Cell Permeable Tre-Recombinase

13 Feb 2012

Abstract excerpt

Over the previous years, comprehensive studies on antiretroviral drugs resulted in the successful introduction of highly active antiretroviral therapy (HAART) into clinical practice for treatment of HIV/AIDS. However, there is still need for new therapeutic approaches, since HAART cannot eradicate HIV-1 from the infected organism and, unfortunately, can be associated with long-term toxicity and the development of...

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PMID: 22348110
DOI: 10.1371/journal.pone.0031576

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