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Article

Development of an inducible pol III transcription system essentially requiring a mutated form of the TATA-binding protein.

Nucleic acids research - 15 Apr 2001

Meissner W, Rothfels H, Schäfer B, Seifart K

Abstract excerpt

We attempted to devise a transcription system in which a particular DNA sequence of interest could be inducibly expressed under the control of a modified polymerase III (pol III) promoter. Its activation requires a mutated transcription factor not contained endogenously in human cells. We constructed such a promoter by fusing elements of the beta-lactamase gene of Escherichia coli, containing a modified TATA-box...

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Identifiers

PMID: 11292839
DOI: 10.1093/nar/29.8.1672
PMCID: PMC31323

Genes

TBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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