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Article

Long-term polarization of microglia upon α-synuclein overexpression in nonhuman primates.

Neuroscience - 19 Apr 2012

Barkholt P, Sanchez-Guajardo V, Kirik D, Romero-Ramos M

Abstract excerpt

We have previously shown that persistent α-synuclein overexpression in ventral midbrain of marmoset leads to a distinctive neurodegenerative process and motor defects. The neurodegeneration was confined to caudate putamen dopaminergic fibers in animals overexpressing wild-type (wt) α-synuclein. H...

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Identifiers

PMID: 22342967
DOI: 10.1016/j.neuroscience.2012.02.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22342967-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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