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Article

Collagen type 1A1, type 3A1, and LOXL1/4 polymorphisms as risk factors of pelvic organ prolapse.

BMC research notes - 7 Jan 2021

Ashikari Asuka, Suda Tetsuji, Miyazato Minoru

Abstract excerpt

OBJECTIVE: Collagen and elastin are the main components of the female pelvic tissue. We investigated whether single nucleotide polymorphisms (SNPs) of collagen type 1 alpha 1 (COL1A1), collagen type 3 alpha 1 (COL3A1), and lysyl oxidase-like (LOXL) 1 and 4 were associated with the onset of pelvic organ prolapse (POP) in Japanese women. Fifty-two women with POP and 28 women without POP were included. SNPs were...

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Identifiers

PMID: 33413618
DOI: 10.1186/s13104-020-05430-6
PMCID: PMC7792296

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