Association of a common LAMA5 variant with anthropometric and metabolic traits in an Italian cohort of healthy elderly subjects.

doi:10.1016/j.exger.2010.10.003

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Article

Association of a common LAMA5 variant with anthropometric and metabolic traits in an Italian cohort of healthy elderly subjects.

Experimental gerontology - 1 Jan 2011

De Luca Maria, Crocco Paolina, Wiener Howard, Tiwari Hemant K, Passarino Giuseppe, Rose Giuseppina

Abstract excerpt

Laminins are large heterotrimeric glycoproteins found in basement membranes where they play an essential role in cell-matrix adhesion, migration, growth, and differentiation of various cell types. Previous work reported that a genetic variant located within the intron 1 of LAMA5 (rs659822) was associated with anthropometric traits and HDL-cholesterol levels in a cohort of premenopausal women. The present study...

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PMID: 20951195
DOI: 10.1016/j.exger.2010.10.003
PMCID: PMC2998567

Genes

LAMA5

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